Hepatitis C and Cancer
The newest kid in the block seeking treatment using marijuana is hepatitis c, the chronic, viral liver disease. Here is the old view: marijuana to be avoided:
Here is the latest: may be therapeutic:
This article summarizes both positions:
Not all states that have legalized medical marijuana explicitly mention hep c as a qualifying condition, but it can be included in the chronic disease category if the qualifying doctor is sympathetic to the latest twist. Is this yet another example of the protective effects of the cannabinoid system?
‘It is interesting to observe how these CB2 receptors are located in the liver cells of patients with active cirrhosis, but not in the liver cells of people not suffering from cirrhosis. This observation appears to indicate that the endocannabinoid system plays a protective role in this illness. The mechanism that the endocannabinoid system uses to reduce the fibrosis process is similar to the one it uses to control cancer cells. This process consists of the inhibition of cell growth and the induction of apoptosis, or programmed cell death.’ from
As mentioned above, that the same mechanisms that protects the liver, namely the inhibition of cell growth and apoptosis, are also anti tumor is expand in the article below from the National Cancer Institute. This article cites several studies on a variety of cancers relating to positive cancer outcomes including the inhibition of angiogenesis and increase uptake by cancer cells by cytotoxic agents.
This is an excellent review of the cannabinoid signaling pathways involved in tumor suppression.